Project information
Early diagnostics of Cardiovascular Diseases
- Project Identification
- MSM141100004
- Project Period
- 1/1999 - 1/2004
- Investor / Pogramme / Project type
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Ministry of Education, Youth and Sports of the CR
- Research Intents
- MU Faculty or unit
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Faculty of Medicine
- prof. MUDr. Bohumil Fišer, CSc.
- prof. MUDr. Jarmila Siegelová, DrSc.
- Keywords
- Cardiovascular diseases; Early stages; Secondary prevention; Basic phenomenes; Atherosclerosis; Vasculopathies; Autonomic nervous system; Myocardial cell; Sudden death; Cardiomyopathies; Heart transplant
An longterm research directed to the detection of early stages of cardiovascular diseases and to a secondary prevetion what has a broad epidemiological consequences. Both clinical and experimental institutions who would tightly collaborate should be involved. This way it might be realistic to evaluate basic features with their next impacts for the clinical medicine. The research should be targeted on these areas: The development of atherosclerosis and of other vasculopathies with outcomes for a prevention of ischemic episodes and for rational solutions of unstable angina. The system of management of circulation including assessments of the autonomic nervous system and biological rhytms with possibilities to influence that. The electrophysiology of the myocardial cell, a genetic stratification of a sudden death§s risk, possibilities to prevent it by various therapeutic modalities and a precision of this indications. The detection of early stages of cardiomyopathies by means of genetic methods.
Publications
Total number of publications: 991
2002
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Pharmaxological and Industrial Challenge: Deciphering Extracircadian Rhytmic Signatures in us
Scripta Medica, year: 2002, volume: 75, edition: 2
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Polymorphisms in ACE and angiotensinogen genes in chronic heart failure
Journal of Hypertension, year: 2002, volume: 20, edition: 4
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Polymorphisms in inflammatory genes (TNFalpha, TNFbeta and TNFalpha-converting enzyme) in chronic heart failure
Year: 2002, type: Conference abstract
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Prevention of apoptosis by deferoxamine during 4 hours of cold cardioplegia and reperfusion: in vitro study of isolated working rat heart model
Pathophysiology, year: 2002, volume: 9, edition: 1
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Prognosis of patients with chronic coronary artery disease and severe left ventricular dysfunction. The importance of myocardial viability.
Europ J Echocardiography, year: 2002, volume: 3, edition: Suppl.I
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Prognostic importance of myocardial viability in revascularized patients with coronary artery disease and left ventricular dysfunction
Europ Heart J, year: 2002, volume: 23, edition: Abstr.Supp
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Prognoza nemocných s chronickou ICHS a těžkou poruchou funkce levé komory. Význam hodnocení viability myokardu
Cor Vasa, year: 2002, volume: 44, edition: 4
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PULSE PRESSURE AND RESISTANCE OF CAROTID ARTERIAL BLOOD VESSELS IN ESSENTIAL HYPERTENSION. Abstracts.
Acta Physiol. Hungarica, year: 2002, volume: 89, edition: 1-3
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PULSE PRESSURE, BAROREFLEX SENSITIVITY AND INTIMA MEDIA THICKNESS (IMT) IN PATIENTS WITH ESSENTIAL HYPERTENSION UNDER THERAPY. Abstracts.
Sborník abstrakt , Kongres MEFA 2002, year: 2002
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Pulsový tlak, baroreflexní senzitivita a tloušťka stěny karotidy (IMT) u léčených pacientů s esenciální hypertenzí, abstrakt.
Cor et Vasa, year: 2002, volume: 2002, edition: 4