Project information
National institute for cancer research
(NÚVR)
- Project Identification
- LX22NPO5102
- Project Period
- 6/2022 - 12/2025
- Investor / Pogramme / Project type
-
Ministry of Education, Youth and Sports of the CR
- national recovery plan
- 5.1 EXCELES
- MU Faculty or unit
-
Faculty of Medicine
- prof. RNDr. Ondřej Slabý, Ph.D.
- Mgr. Klára Baďurová
- MUDr. Viera Bajčiová, CSc.
- MUDr. Denisa Bakešová
- Mgr. Andrej Bešše, Dr. sc. nat.
- Mgr. Lenka Bešše, Ph.D.
- Ing. Eva Blahová, Ph.D.
- Mgr. Júlia Bohošová, Ph.D.
- Mgr. Michaela Bosáková, Ph.D.
- Mgr. Pavla Bouchalová, Ph.D.
- Mgr. Jana Bruknerová
- Ing. Daniel Buša
- Aleksandra Anna Czyrek, PhD
- PharmDr. Martin Čulen, Ph.D.
- Mgr. Adéla Dostálová
- prof. MUDr. Michael Doubek, Ph.D.
- Mgr. Barbara Dvořáčková, Ph.D.
- Mgr. Bohumil Fafílek, Ph.D.
- Mgr. Zuzana Feketová, Ph.D.
- Mgr. Alena Homolová, Ph.D.
- Mgr. Jan Hýl
- prof. RNDr. Mgr. Marie Jarošová, CSc.
- Mgr. Martina Jelínková
- Ing. Robin Jugas, Ph.D
- Mgr. Beáta Katrincsáková, Ph.D.
- RNDr. Ingrid Kováčová
- Mgr. Kateřina Koždoňová
- MUDr. Marie Kramárová
- Marcela Krejčí
- RNDr. Pavel Krejčí, Ph.D.
- Helene Sorum Kristiansen
- MUDr. Zuzana Kuttnerová
- MUDr. Michal Kýr, Ph.D.
- Mgr. Petr Lapčík, Ph.D.
- Debora Ledahudcová
- RNDr. Jitka Malčíková, Ph.D.
- prof. MUDr. Jiří Mayer, CSc.
- MUDr. Tomáš Merta
- MUDr. Peter Múdry, Ph.D.
- Mgr. Veronika Navrkalová, Ph.D.
- Hana Novotná
- Mgr. Šárka Pavlová, Ph.D.
- Mgr. Lukáš Pečinka, Ph.D.
- Mgr. Karla Plevová, Ph.D.
- Barbora Podhajská
- Mgr. Petra Pokorná
- Helena Poláková
- MUDr. Kristýna Polášková, Ph.D.
- Mgr. Ing. Jakub Paweł Porc
- Mgr. Vendula Rašková, Ph.D.
- MUDr. Ondřej Rohleder
- doc. MUDr. Peter Rohoň, Ph.D.
- Ing. Mgr. Michaela Ručková
- Mgr. Tereza Růžičková
- Bc. Petra Sedláková
- Mgr. Lenka Sedlaříková, Ph.D.
- Mgr. Dagmar Smitalová, Ph.D.
- Mgr. Bc. Karolína Smolková
- Mgr. Radim Sonnek
- Mgr. Kateřina Staňo Kozubík, Ph.D.
- Mgr. Kamila Stránská, Ph.D.
- Ing. Michaela Stroblová, Ph.D.
- Mgr. Hana Svozilová, Ph.D.
- Kateřina Svozilová
- doc. RNDr. Sabina Ševčíková, Ph.D.
- prof. MUDr. Jaroslav Štěrba, Ph.D.
- MUDr. Martin Štěrba
- MUDr. Silvie Šurková
- MUDr. Pavel Tinka
- MUDr. Terézia Tureková
- Dr. Suzanne Dawn Turner
- Mgr. Stjepan Uldrijan, CSc.
- Ing. Natália Vadovičová
- doc. RNDr. Petr Vaňhara, Ph.D.
- Mgr. Marek Večeřa
- MUDr. Klára Vejmělková, Ph.D.
- Mgr. Jana Vepřková
- Mgr. Bc. Monika Vlachová
- Mgr. Petra Vychytilová, Ph.D.
- MUDr. Danica Zapletalová, Ph.D.
- Miroslava Žítková, DiS.
- Other MU Faculty/Unit
-
Faculty of Science
- prof. Mgr. Vítězslav Bryja, Ph.D.
- doc. Mgr. David Bednář, Ph.D.
- doc. Mgr. Petr Beneš, Ph.D.
- Mgr. Karolína Bořánková, Ph.D.
- doc. Mgr. Pavel Bouchal, Ph.D.
- Mgr. Anežka Celá
- Mgr. Štěpán Čada
- Mgr. Kristína Gömöryová, Ph.D.
- Faraneh Haddadi
- RNDr. Vendula Hlaváčková Pospíchalová, Ph.D.
- Mgr. Jana Horáčková
- Mgr. Šárka Hrachovinová
- RNDr. Petr Chlapek, DiS., Ph.D.
- Mgr. Blanka Jančeková, Ph.D.
- Mgr. Pavlína Janovská, Ph.D.
- Mgr. Aneta Jarošková
- MUDr. Marta Ježová, Ph.D.
- Darja Klementová
- Mgr. Lucia Knopfová, Ph.D.
- Mgr. Jiří Kohoutek, Ph.D.
- Mgr. Petra Kompaníková
- Mgr. Lucia Krahulcová
- Mgr. Marek Kravec, Ph.D.
- Johana Marešová
- Stanislav Mazurenko, PhD
- Mgr. Jiřina Medalová, Ph.D.
- MUDr. Jan Mičan
- Mgr. Tereza Michalíková
- Mgr. Antónia Mikulová
- Mgr. Jarmila Navrátilová, Ph.D.
- doc. RNDr. Jakub Neradil, Ph.D.
- Ing. Zuzana Orlová
- Mgr. Martin Pavlíček
- Mgr. Hana Plešingerová, Ph.D.
- Mgr. Daniel Pluskal
- Mgr. Jana Pokludová
- Mgr. Petra Procházková
- Ing. Zuzana Prouzová, Ph.D.
- Mgr. Matěj Přikryl
- Viktor Pushkarov
- Bc. Janka Rakytová
- Mgr. Andrea Rousová
- Mgr. Kamila Říhová, Ph.D.
- Mgr. Eva Slabáková, Ph.D.
- Mgr. Stanislava Sladeček, Ph.D.
- Mgr. Karel Souček, Ph.D.
- Mgr. Lukáš Sourada
- Bc. Karolína Stöhrová
- Mgr. Bc. Alan Strunga
- Ing. Jan Šimoník
- RNDr. Jan Škoda, Ph.D.
- Dagmar Štodtová
- Ing. Jan Velecký
- Ing. Jan Verner, Ph.D.
- prof. RNDr. Renata Veselská, Ph.D., M.Sc.
- Mgr. Olga Vondálová Blanářová, Ph.D.
- Other MU Faculty/Unit
-
Central European Institute of Technology
- prof. RNDr. Šárka Pospíšilová, Ph.D.
- Mgr. Petra Babková
- Bc. et Bc. Erika Bajusová
- Nilanjan Banerjee, Ph.D.
- Mgr. Tereza Deissová
- Mgr. Lenka Dostálová
- Mgr. Kryštof Hlaváč
- Mgr. Lenka Humpolíková Adámková, Ph.D.
- Mgr. Libuše Janská, BA
- Bc. Jana Jedličková
- prof. MUDr. Zdeněk Kala, CSc.
- doc. MUDr. Tomáš Kazda, Ph.D.
- doc. MUDr. Igor Kiss, Ph.D., MBA
- Mgr. Filip Kledus
- Mgr. Kateřina Koželková
- Mgr. Adriana Ladungová
- Mgr. Táňa Macháčková, Ph.D.
- Ludmila Marková
- prof. MUDr. Mgr. Marek Mráz, Ph.D.
- Mgr. Jana Orlíčková
- Mgr. Karol Pál, Ph.D.
- Mgr. Hana Pálová, Ph.D.
- Barbora Petrlíková
- Mgr. Lenka Radová, Ph.D.
- Mgr. František Siegl
- prof. MUDr. Marek Svoboda, Ph.D.
- doc. Mgr. Jiří Šána, Ph.D.
- Mgr. Michal Šmída, Dr. rer. nat.
- Mgr. Jiří Štika, Ph.D.
- Mgr. Karolína Trachtová
- doc. Mgr. Lukáš Trantírek, Ph.D.
- RNDr. Silvie Trantírková, Ph.D.
- RNDr. Josef Večeřa, Ph.D.
- MVDr. Martina Vodinská
- Keywords
- oncology, cancer, national institute
- Cooperating Organization
-
Institute of Microbiology of the ASCR, v. v. i.
- Responsible person Ing. Jiří Hašek, CSc.
- Responsible person Ing. Miroslava Anděrová, CSc.
- Responsible person Dr. Ing. Jiří Kotek
- Responsible person RNDr. Petr Dráber, DrSc.
- Responsible person prof. RNDr. Jan Konvalinka, CSc.
- Responsible person doc. Ing. Pavel Peterka, Ph.D.
- Responsible person prof. MUDr. Alexi Šedo, DrSc.
- Responsible person prof. MUDr. Martin Procházka, Ph.D.
- Responsible person prof. MUDr. Marek Svoboda, Ph.D.
The aim of the project is to create a nationwide network of collaborating workplaces conducting cutting-edge research in the field of oncology, which will take the form of a "National Institute". The reason for the creation of this authority is that research in oncology is currently not coordinated in any way and is fragmented across institutions.
The establishment of a National Institute for Cancer Research will bring together cutting-edge scientific expertise, tertiary education and relevant medical/health information resources. The thematic complementarity of the individual departments within the National Cancer Research Institute will allow for a comprehensive approach necessary for modern cancer research, concentrating on priority areas of medical education and research in the Czech Republic. Cancer research will thus become much more coordinated, strategic and efficient.
The great advantage of the National Institute is its transformative character, i.e. no new infrastructure will be built (an exception is the necessary construction of the GMP for somatic cell and gene therapy ATMP in pavilion C03), but the development and modernisation of existing capacities and human resources. This approach is highly efficient and financially sustainable in the long term.
The network of collaborating sites will consist of three Nodes (Prague Node - coordinator, Brno Node, Olomouc Node), which will cover the whole Czech Republic. The individual Nodes will be connected through a consortium agreement that defines the frameworks and rules of cooperation.
Sustainable Development Goals
Masaryk University is committed to the UN Sustainable Development Goals, which aim to improve the conditions and quality of life on our planet by 2030.
Publications
Total number of publications: 255
2023
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Exploring the mechanisms of Venetoclax resistence via drug screening and genome-wide CRISPR screening.
Year: 2023, type: Conference abstract
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Expression dynamics of metalloproteinases during mandibular bone formation: association with Myb transcription factor
Frontiers in Cell and Developmental Biology, year: 2023, volume: 11, edition: August 2023, DOI
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Extensive, 3.8 Mb-Sized Deletion of 22q12 in a Patient with Bilateral Schwannoma, Intellectual Disability, Sensorineural Hearing Loss, and Epilepsy
Molecular Syndromology, year: 2023, volume: 14, edition: 5, DOI
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Favorable prognostic significance of membranous β-catenin expression and negative prognostic significance of cytoplasmic β-catenin expression in pancreatic cancer
Neoplasma, year: 2023, volume: 70, edition: 6, DOI
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FOX01-rictor AXIS induces AKT phosporylation during CLL cell adaptation to BCR inhibitors: Implications for combinatorial therapy.
Year: 2023, type: Conference abstract
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FOXO1-RICTOR AXIS induces adaptive increase in AKT activity during BCR inhibitor therapy in CLL: Implications for combination therapy.
Year: 2023, type: Conference abstract
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Foxo1-Rictor axis mediates adaptive increase in Akt activity and cell survival during BCR inhibitor therapy in chronic lymphocytic leukemia.
Year: 2023, type: Conference abstract
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FoxP3 Expression in Tumor-Infiltrating Lymphocytes as Potential Predictor of Response to Immune Checkpoint Inhibitors in Patients with Advanced Melanoma and Non-Small Cell Lung Cancer
Cancers, year: 2023, volume: 15, edition: 6, DOI
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From fish to cells: Establishment of continuous cell lines from embryos of annual killifish Nothobranchius furzeri and N. kadleci
Aquatic Toxicology, year: 2023, volume: 259, edition: June, DOI
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Gemtuzumab ozogamicin plus midostaurin in conjunction with standard intensive therapy for FLT3-mutated acute myeloid leukemia patients - Czech Center experience
Haematologica, year: 2023, volume: 108, edition: 10, DOI