Bacteriophage transduction of mobile genetic elements in methicillin-resistant Staphylococcus aureus

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Authors	DOŠKAŘ Jiří VARGA Marian MAŠLAŇOVÁ Ivana PANTŮČEK Roman MOŠA Marek
Year of publication	2013
Type	Article in Proceedings
Conference	Bacteriophages: Theoretical and Practical Aspects of Their Application in Medicine, Veterinary and Food. Vol. 2
MU Faculty or unit	Faculty of Science
Citation
Web	http://www.congress-bacteriophage.niicmib.ru/index_en.html
Field	Genetics and molecular biology
Keywords	bacteriophage; transduction; horizontal gene transfer; MRSA; mobile genetic elements; antibiotic resistance; lysogeny
Description	This research was aimed at characterizing transduction of mobile genetic elements in methicillin-resistant strains of Staphylococcus aureus. In this work it has been proved that bacteriophages efficiently transferred antibiotic resistance and virulence genes between clinical S. aureus strains. Furthermore, successful transduction was performed using prophages of lysogenic laboratory and clinical strains.
Related projects:	Výzkum stafylokokových bakteriofágových mutant s širokým spektrem hostitelů Molekulární průkaz a analýza invazivních kmenů small colony variants (SCV) a rezistentních kmenů S. aureus od pacientů s cystickou fibrózou