Subnuclear partitioning of rRNA genes between the nucleolus and nucleoplasm reflects alternative epiallelic states
Authors | |
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Year of publication | 2013 |
Type | Article in Periodical |
Magazine / Source | GENES & DEVELOPMENT |
MU Faculty or unit | |
Citation | |
Web | http://0-www.ncbi.nlm.nih.gov.elis.tmu.edu.tw/pmc/articles/PMC3731543/ |
Doi | http://dx.doi.org/10.1101/gad.221648.113 |
Field | Genetics and molecular biology |
Keywords | transcription; gene silencing; DNA methylation; histone deacetylation; chromatin assembly; RNA polymerase I; ribosomal RNA gene |
Description | Eukaryotes can have thousands of 45S ribosomal RNA ( rRNA) genes, many of which are silenced during development.Collectively, the data reveal that rRNA genes occupy distinct but changeable nuclear territories according to their epigenetic state. |
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