Genomic porosity between invasive Chondrostoma nasus and endangered endemic Parachondrostoma toxostoma (Cyprinidae): The evolution of MHC IIB genes

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Authors	VETEŠNÍKOVÁ ŠIMKOVÁ Andrea CIVÁŇOVÁ Kristína GETTOVÁ Lenka GILLES André
Year of publication	2013
Type	Article in Periodical
Magazine / Source	Plos One
MU Faculty or unit	Faculty of Science
Citation
Doi	http://dx.doi.org/10.1371/journal.pone.0065883
Field	Genetics and molecular biology
Keywords	Chondrostoma nasus; Parachondrostoma toxostoma; MHC IIB
Description	Two cyprinid species, Parachondrostoma toxostoma, an endemic threatened species, and Chondrostoma nasus, an invasive species, live in sympatry in southern France and form two sympatric zones where the presence of intergeneric hybrids is reported. To estimate the potential threat to endemic species linked to the introduction of invasive species, we focused on the DAB genes (functional MHC IIB genes) because of their adaptive significance and role in parasite resistance. More specifically, we investigated (1) the variability of MHC IIB genes, (2) the selection pattern shaping MHC polymorphism, and (3) the extent to which trans-species evolution and intergeneric hybridization affect MHC polymorphism.
Related projects:	Hostitelsko-parazitické interakce v hybridních systémech kaprovitých ryb ECIP - Evropské centrum ichtyoparazitologie