The Molecular Typing Data of Recently Identified Subtype 11q/j of Treponema pallidum subsp. pallidum Suggest Imported Case of Yaws.
| Title in English | The molecular typing data of recently identified subtype 11q/j of treponema pallidum subsp. pallidum suggest imported case of yaws |
|---|---|
| Authors | |
| Year of publication | 2014 |
| Type | Article in Periodical |
| Magazine / Source | Sexually transmitted diseases |
| MU Faculty or unit | |
| Citation | |
| Field | Epidemiology, infectious diseases and clinical immunology |
| Keywords | WHOLE GENOME SEQUENCE; STRAINS; SYPHILIS; PERTENUE; GENE; CONSERVATION; DIFFER |
| Description | In the article ‘‘Molecular Subtyping of Treponema pallidum in Paris, France,’’ published in Sexually Transmitted Diseases journal (Vol. 40, No. 8, August 2013), Grange et al.1 identified 3 subtypes that are sporadically present in the human population, that is, subtypes 11q/j, 14d/d, and 15d/f. Interestingly, subtype 11q/j showed a unique typing pattern ‘‘q’’ corresponding to a new restriction profile after MseI digestion of the tprE,G,J genes (Centers for Disease Control and Prevention [CDC] typing system)2 and ‘‘j’’ corresponding to a new sequence type within the 83-basepair region of the tp0548 gene (enhanced CDC typing system).3 This genital specimen was isolated from an HIV-negative MSM (men who have sex with men) patient with diagnosed primary syphilis. |
| Related projects: |