Doxorubicin and liposomal doxorubicin affect microRNA expression in rat right ventricles

Authors

NOVÁK Jan STRAČINA Tibor NOVÁKOVÁ Marie

Year of publication 2014
Type Conference abstract
Citation
Description In order to better understand the acute effects of doxorubicin (DOX) and liposomal DOX on the heart, analysis of 4 selected microRNAs (miR-208a/146a/216b/let-7g) that may be involved in DOX-induced cardiotoxicity was performed, both in the left and right ventricles of the Wistar rat exposed to one dose of DOX/liposomal DOX. This acute administration of mentioned drugs affects stightly expression of selected microRNAs, especially in right ventricle.
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