Kardiovaskulární nežádoucí účinky protinádorových léčiv
| Title in English | Cardiovascular side effects of antitumor drugs |
|---|---|
| Authors | |
| Year of publication | 2014 |
| Type | Article in Periodical |
| Magazine / Source | Onkologie |
| MU Faculty or unit | |
| Citation | |
| Field | Oncology and hematology |
| Keywords | antitumor drugs; cardiovascular side effects; cardioprotection |
| Description | Cancer represents the second most frequent cause of mortality in the Czech Republic as well as in all other EU member countries. In 2010, there were 82 606 new cases of malignant tumours reported to National oncology registry of the Czech Republic, which means about 4% increase as compared to 2009. Taking into account that cardiovascular diseases are foremost reason of death in European countries and cardiotoxicity of chemotherapy is well known, there is a need to search for new cardioprotective techniques and improvements of actual anti-tumour protocols. This review focuses on cardiotoxic effects of main groups of cytostatic drugs and on potential methods decreasing these adverse side effects. |
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