Dynamické metody kvantitativního testování senzitivity
| Title in English | Dynamic Methods of Quantitative Sensory Testing |
|---|---|
| Authors | |
| Year of publication | 2016 |
| Type | Article in Periodical |
| Magazine / Source | Česká a Slovenská neurologie a neurochirurgie |
| MU Faculty or unit | |
| Citation | |
| Field | Neurology, neurosurgery, neurosciences |
| Keywords | pain perception; nociceptive pain; neuropathic pain; temporal summation; conditioned pain modulation; pain measurement; sex factors; age factors |
| Attached files | |
| Description | Background: So called “dynamic quantitative sensory methods” (dQST) represent relatively new QST application which enables to objectify certain mechanisms of pain processing, e.g. central integration or descending control. Their dysfunction may contribute to the development of chronic painful conditions. dQST methods proved the potential to predict the development of chronic postoperative pain. Conditioned pain modulation (CPM) and temporal summation (TS) are the most commonly used dQST tests. Patients and methods: The CPM and TS testing was performed in a group of 77 healthy volunteers (47 women tested in the ovulatory phase of the menstrual cycle, 30 men, age range 19–73) using thermal pain stimuli. Effi ciency of CPM and TS mechanism including age and gender infl uence was evaluated. Results: Effi cient CPM was found in 84% of healthy volunteers. In remaining 16%, the ineffi ciency was mainly due to low intensity of testing or modulatory stimuli. Based on the temperature used, effi cient TS mechanism was found in 92% or 98% of healthy individuals. Women in the ovulatory phase of the menstrual cycle showed signifi cantly more effi cient CPM comparing to men. No sex diff erences of TS testing were found. Age had no signifi cant eff ect on the CPM or TS mechanism in our group of healthy voluteers. Conclusions: Our study has verifi ed the applicability of CPM and TS algorithms used. Women in ovulatory phase of the menstrual cycle show increased anti-nociceptive setting comparing to men. No signifi cant eff ect of age on central modulation of pain perception has been found in pain-free healthy individuals. |
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