Thermostable FGF2 Polypeptide, Use Thereof

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Authors	DVOŘÁK Petr KREJČÍ Pavel BÁLEK Lukáš EISELLEOVÁ Lívia KONEČNÁ Žaneta DVOŘÁK Pavel BEDNÁŘ David BREZOVSKÝ Jan ŠEBESTOVÁ Eva CHALOUPKOVÁ Radka ŠTĚPÁNKOVÁ Veronika VAŇÁČEK Pavel PROKOP Zbyněk DAMBORSKÝ Jiří BOSÁKOVÁ Michaela
Year of publication	2020
Type	Patent
MU Faculty or unit	Faculty of Science
Publisher	European Patent Office
State	Germany
Patent's number	EP3380508
Web	https://worldwide.espacenet.com/patent/search/family/054754475/publication/EP3380508B1?q=pn%3DEP3380508B1
Description	The present invention relates to engineered Fibroblast Growth Factor 2 (FGF2, bFGF) having improved thermal stability compared to the wild-type and the use thereof in the cell biology research, regenerative medicine and related medical applications or cosmetics. The present invention further relates to a culture medium comprising FGF2 suitable for culturing a human pluripotent stem cells involving both human embryonic stem cells and induced pluripotent stem cells.
Related projects:	Centrum pro výzkum toxických látek v prostředí Centrum pro výzkum toxických látek v prostředí