Variability in selected candidate genes for recurrent aphthous stomatitis: a pilot study

Slezáková,  Simona; Bořilová Linhartová,  Petra; Bártová, Jiřina; Petanová, Jitka; Kuklínek,  Pavel; Fassmann,  Antonín; Izakovičová Hollá,  Lydie

Variability in selected candidate genes for recurrent aphthous stomatitis: a pilot study

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Authors	VALOVÁ Simona BOŘILOVÁ LINHARTOVÁ Petra BÁRTOVÁ Jiřina PETANOVÁ Jitka KUKLÍNEK Pavel FASSMANN Antonín IZAKOVIČOVÁ HOLLÁ Lydie
Year of publication	2016
Type	Conference abstract
MU Faculty or unit	Faculty of Medicine
Citation
Description	The aim of this study was to investigate six single nucleotide polymorphisms (SNPs) in IL-6, interleukin-6 receptor (IL-6R) and MMP-9 genes in patients with RAS and healthy controls in the Czech Caucasian population. Although, in contrast to previous studies, no significant associations between IL-6 and IL-6R gene variants and RAS were found, our pilot results indicated that MMP-9 gene variability could affect the risk of developing recurrent aphthous stomatitis in the Czech Caucasian population.
Related projects:	Centrum orofaciálního vývoje a regenerace Změny imunologické reaktivity u pacientů s recidivujícími aftami Analýza klinických, mikrobiálních a genetických faktorů v etiopatogenezi vybraných patologických stavů v dutině ústní