Studium vlivu mědi na cytotoxicitu wedelolaktonu v buňkách karcinomu prsu pomocí (SALD) ICP MS

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Title in English	Study of copper effect on wedelolactone cytotoxicity in breast cancer cells by (SALD) ICP MS
Authors	STIBOREK Marek NEHYBOVÁ Tereza BENEŠ Petr KANICKÝ Viktor PREISLER Jan
Year of publication	2017
Type	Conference abstract
MU Faculty or unit	Faculty of Science
Citation
Description	Performed experiments showed the subsequent cells treatment by Cu (II) and wedelolactone can significantly enhance the wedelolactone cytotoxicity. Considerable cytotoxicity increment was observed for cells with transfected hCtr1 gene. On the other hand, the simultaneous cells treatment led to reduction of wedelolactone cytotoxicty. This effect can be caused by Cu (II)-wed complex inability to penetrate through the cytoplasmic cell membrane.
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