Changes in lipid and amino acid levels during pregnancy and early postpartum period in pregnancy complicated by gestational diabetes mellitus
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| Year of publication | 2017 |
| Type | Conference abstract |
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| Description | The increasing prevalence of gestational diabetes mellitus (GDM) poses a risk for permanent diabetes development in future life for both mother and child. We hypothesize, that changes in non-esterified fatty acids (NEFAs) and amino acids (AAs) in plasma previously associated with type 2 diabetes development may reflect more severe abnormalities in insulin secretion and sensitivity and thus may point at more severe disturbance in glucose tolerance during pregnancy. The aims of this study were to determine NEFAs (C12:0 to C22:6) and all proteinogenic and several nonessential AAs during pregnancy and postpartum period in women with GDM and those with physiological pregnancy and to study the relationships between selected metabolites and anthropometrical and biochemical data. |
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