The 9aaTAD Activation Domains in the Yamanaka Transcription Factors Oct4, Sox2, Myc, and Klf4

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Authors	PISKÁČEK Martin OTAŠEVIČ Tomáš REPKO Martin KNIGHT Andrea
Year of publication	2021
Type	Article in Periodical
Magazine / Source	Stem Cell Reviews and Reports
MU Faculty or unit	Faculty of Medicine
Citation
Web	https://link.springer.com/article/10.1007/s12015-021-10225-8
Doi	http://dx.doi.org/10.1007/s12015-021-10225-8
Keywords	Stem cell; iPSCs; SoxE; Sox9; KIX; CBP; MED15
Description	Somatic cells can be reprogrammed by the Yamanaka factors Oct4, Sox2, Myc and Klf4 into pluripotent stem cells. Previously, we have identified the activation domain 9aaTAD in the related SP, KLF and SOX activators. In this study, we searched for the 9aaTAD domains in Yamanaka factors, which are activators of transcription.
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