Diversity of MHC IIB genes and parasitism in hybrids of evolutionarily divergent cyprinoid species indicate heterosis advantage

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Authors	ŠIMKOVÁ Andrea GETTOVÁ Lenka CIVÁŇOVÁ Kristína SEIFERTOVÁ Mária JANÁČ Michal VETEŠNÍK Lukáš
Year of publication	2021
Type	Article in Periodical
Magazine / Source	Scientific reports
MU Faculty or unit	Faculty of Science
Citation
Web	https://doi.org/10.1038/s41598-021-96205-x
Doi	http://dx.doi.org/10.1038/s41598-021-96205-x
Keywords	MHC IIB genes; heterosis advantage; cyprinid fish
Description	The genes of the major histocompatibility complex (MHC) are an essential component of the vertebrate immune system and MHC genotypes may determine individual susceptibility to parasite infection. In the wild, selection that favors MHC variability can create situations in which interspecies hybrids experience a survival advantage. We assessed MHC IIB genetic variability and its potential relationships to hosts' ectoparasite communities.
Related projects:	Genetická disrupce u mezidruhových hybridů kaprovitých ryb: její dopad na fitness-asociované znaky, metabolické náklady, imunitu a parazitární zátěž