Chirurgická terapie mozkových metastáz

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Title in English Surgical treatment of brain metastases
Authors

VYBÍHAL Václav FADRUS Pavel SMRČKA Martin ROŠKOVÁ Ivana DUBA Miloš NEUMAN Eduard SOVA Marek KAZDA Tomáš VEČEŘA Marek ŠÁNA Jiří

Year of publication 2021
Type Article in Periodical
Magazine / Source Onkoloigie
MU Faculty or unit

Faculty of Medicine

Citation
Web https://www.solen.cz/artkey/xon-202105-0005_chirurgicka_terapie_mozkovych_metastaz.php?back=%2Fsearch.php%3Fquery%3Dfarmakoterapie%252520v%252520t%2525EChotenstv%2525ED%26sfrom%3D390%26spage%3D30
Keywords brain metastasis; resection; radiotherapy; radiosurgery
Description Brain metastases are a serious complication of cancer. There has been an increase in the radicality and safety of resection procedures due to advances in brain imaging methods, perioperative electrophysiological monitoring and instrumentation, while reducing surgical mortality and morbidity. Surgical resection is still considered the first therapeutic option. It is indicated mainly in patients with solitary brain metastasis in an accessible location, in good clinical condition and with a favorable prognosis. It is relatively contraindicated in the case of uncontrolled cancer, poor clinical condition, in the case of radiosensitive tumors a poor prognosis and the presence of more than three brain metastases. It is possible to surgically treat two or three metastases, which may be debatable in some aspects. In a similar way it is for recurrent metastases, where unambiguous general recommendations are not defined, and an individual approach is preferred, taking into account a number of prognostic factors.
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