Oxidation processes of N-methylguanines
| Authors | |
|---|---|
| Year of publication | 2021 |
| Type | Article in Proceedings |
| Conference | XL. Moderní elektrochemické metody |
| MU Faculty or unit | |
| Citation | |
| Web | https://www.bestservis.eu/images/file/Sbornik_metody21.pdf |
| Keywords | Guanine; N-methylated guanine; Oxidation process; Voltammetry; HOMO (SOMO) energy; DFT methods; Epigenetic modification |
| Description | The oxidation processes of N-methylguanines were investigated in both experimental and theoretical way. Voltammetric oxidation potentials of guanine and its methyl analogues, acquired on polymer pencil graphite electrode (pPeGE), were compared with the HOMO (SOMO) energies calculated by density functional (DFT) methods. Our study contributes to understanding not only the oxidation processes of methylated guanines but also their role in epigenetics. |
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