Novel potential histone deacetylase inhibitors and their proapoptotic effects in cancer cells
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| Year of publication | 2022 |
| Type | Appeared in Conference without Proceedings |
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| Description | Our research studied the biological activity of new derivates of hydroxamic acids as potential histone deacetylase inhibitors designed and synthesized by the Department of Chemical Drugs, Faculty of Pharmacy, Masaryk University. In particular, our study was focused on evaluating their potential to affect histone acetylation and to induce apoptosis in the monocytic leukemia cell line compared with vorinostat. |
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