Olfactory Bulbectomy Model of Depression Lowers Responding for Food in Male and Female Rats: The Modulating Role of Caloric Restriction and Response Requirement

Warning

This publication doesn't include Institute of Computer Science. It includes Faculty of Medicine. Official publication website can be found on muni.cz.

Authors	FATTORE Liana AMCHOVÁ Petra FADDA Paola RUDÁ Jana
Year of publication	2023
Type	Article in Periodical
Magazine / Source	BIOMEDICINES
MU Faculty or unit	Faculty of Medicine
Citation
Web	https://www.mdpi.com/2227-9059/11/9/2481
Doi	http://dx.doi.org/10.3390/biomedicines11092481
Keywords	olfactory bulbectomy; depression; reward; self-administration; sex; strain
Description	In summary, this study showed that bulbectomy significantly reduces operant responding and food intake in male and female Sprague–Dawley rats while inducing a mild reducing effect only in the Wistar strain.
Related projects:	Preclinical and clinical research in pharmacokinetics, neuropsychopharmacology and personalized pharmacotherapy in oncology