Laboratoře analýzy mikrobiomu - ušní, nasální a orální bakteriom
| Title in English | Laboratories for microbiome analysis - ear, nasal, and oral bacteriome |
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| Year of publication | 2023 |
| Type | Conference abstract |
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| Description | The research activities of the RECETOX Centre are supported by state-of-the-art research infrastructure, which is partially centralised in separate units, the so-called core facilities. The research infrastructure operates on the principle of "open access", providing its capacity to internal and external users from both academia and industry. Our Central Laboratories also include a core facility, the Microbiome Analysis Laboratory, where we analyse the microbiome of human, animal and environmental samples using modern next-generation sequencing methods. In addition to actual sample analysis, we offer assistance with metagenomic study design, evaluation and interpretation of sequencing data. The human microbiome, or the set of genetic information of the microbiota, is specific to the location from which it originates. In the orofacial region, the oral microbiome has been the most studied to date, with significantly more studies beginning to focus on the nasal and nasopharyngeal microbiome at the time of the Covid-19 pandemic. There may be specific relationships between the oral and nasal microbiome and the ear microbiome, where there are interactions, particularly in young children. The microbiome of the ear, not only the external but also the middle ear, has been the focus of our research in patients with acute or chronic otitis media. |
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