RBP-Tar – a searchable database for experimental RBP binding sites

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Authors	GREŠOVÁ Katarína RAČEK Tomáš MARTINEK Vlastimil ČECHÁK David SVOBODOVÁ Radka ALEXIOU Panagiotis
Year of publication	2024
Type	Article in Periodical
Magazine / Source	F1000Research
MU Faculty or unit	Central European Institute of Technology
Citation
web	https://f1000research.com/articles/12-755/v2
Doi	http://dx.doi.org/10.12688/f1000research.131014.2
Keywords	RNA Binding Proteins; CLIP; RBP; Web-server
Description	RNA-binding proteins (RBPs) play a critical role in regulating gene expression by binding to specific sites on RNA molecules. Identifying these binding sites is crucial for understanding the many functions of RBPs in cellular function, development and disease. Current experimental methods for identifying RBP binding sites, such as ultra-violet (UV) crosslinking and immunoprecipitation (CLIP), and especially the enhanced CLIP (eCLIP) protocol, were developed to identify authentic RBP binding sites experimentally.
Related projects:	e-Infrastruktura CZ