Změny závislosti na metamfetaminu u potkanů vlivem serotonergik a kanabinoidů
| Title in English | Changes of methamphetamine dependence in rats caused by serotonergics and cannabinoids |
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| Authors | |
| Year of publication | 2000 |
| Type | Article in Proceedings |
| Conference | Zborník abstraktov - Česká a Slovenská študentská vedecká konferencia, Košice, SR, 8. - 10. 11. 2000 |
| MU Faculty or unit | |
| Citation | |
| Field | Pharmacology and pharmaceutical chemistry |
| Description | Changes of methamphetamine intake followed the pretreatment with serotonergics and cannabinoids were studied in the model "i.v. drug self-administration" in rats. The exogenous facilitation of neurotransmitter functions of serotonin (e.g. by fluoxetine) in the brain supressed the intake of drug. The incresed intake of methamphetamine was observed after the pretreatment with the cannabinoid agonists, on the contrary the cannabinoid antagonist caused the opposite effect. |
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