Protopine hydrochloride

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Authors

DOSTÁL Jiří ŽÁK Zdirad NEČAS Marek SLAVÍK Jiří POTÁČEK Milan

Year of publication 2001
Type Article in Periodical
Magazine / Source Acta Crystallographica Section C
MU Faculty or unit

Faculty of Medicine

Citation
Field Organic chemistry
Keywords protopine hydrochloride
Description Protopine hydrochloride is the salt of isoquinoline alkaloid protopine. It is formed by the action of diluted hydrochloric acid on protopine free base. The N-methyl and hydroxyl groups are in the trans configuration in the quinolizine ring. The central quinolizine C-N bond is unusually long (1.579 A). The crystal is a racemate.
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