Distribution of the RAGE gene polymorphisms in patients with chronic periodontitis: a preliminary study

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Authors	IZAKOVIČOVÁ HOLLÁ Lydie KAŇKOVÁ Kateřina FASSMANN Antonín BUČKOVÁ Dana HALABALA Tomáš ZNOJIL Vladimír VANĚK Jiří
Year of publication	2001
Type	Article in Periodical
Magazine / Source	J Periodontol
MU Faculty or unit	Faculty of Medicine
Citation
Field	ORL, ophthalmology, stomatology
Keywords	gene; polymorphism; RAGE; periodontitis
Description	Periodontal diseases are viewed today as multifactorial problems that are initiated and sustained by bacteria but significantly modified by the body's response to bacterial plaque. Recent study suggested that RAGE (receptor for advanced glycation end products) could be involved in the pathophysiology of periodontitis. The aim of this study was to investigate a possible association of three common polymorphisms in the RAGE gene with adult periodontitis.
Related projects:	Molecular pathophysiology of multigene diseases