Vztah TaqI A polymorfizmu genu pro DRD2 k alkoholizmu: podvod 20. století?
Title in English | The relationship between the TaqI A polymorphism of the DRD2 gene and alcoholism: deceit of the XX. century? |
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Authors | |
Year of publication | 2001 |
Type | Article in Periodical |
Magazine / Source | Psychiatrie |
MU Faculty or unit | |
Citation | |
Field | Genetics and molecular biology |
Keywords | alcoholism DRD2 polymorphism |
Description | We tried to assess the association between the TaqI A polymorphism of DRD2 gene and the alcohol dependence in the group of 295 subjects (164 controls and 131 alcoholics), unrelated Caucasians from the Czech Republic. Any association between TaqI A polymorphism and alcohol dependence was detected. However, we find some errors in the methodology of some studies that publicised about significant association of the TaqI A polymorphism to the alcohol dependence. These errors are discussed in the introduction. We propose a new reappraisal of these studies. |
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