Alkoholizmus a interleukin 6

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Title in English	Alcoholism and IL-6
Authors	ŠERÝ Omar HLADILOVÁ Renáta HŘÍBKOVÁ Hana HLOUŠKOVÁ Renáta NOVOTNÝ Miroslav ZVOLSKÝ Petr
Year of publication	2001
Type	Article in Periodical
Magazine / Source	Psychiatrie
MU Faculty or unit	Faculty of Science
Citation
Field	Physiology
Keywords	IL-6 alcoholism association polymorphism
Description	Cytokines play the important role in the CNS in the modulations of dopaminergic, serotonergic, noradrenergic and cholinergic systems. From this point of view, the gene for IL-6 is a possible candidate gene of the dispositions to the alcohol dependence. We investigated the relationship between the G/C -174 polymorphism of the IL-6 gene and alcohol dependence in 121 alcoholics and 84 control subjects. No significant difference in allele frequencies between alcoholic group and control group was found for this polymorphic site.
Related projects:	Genetic study of alcohol dependence : detection of the association between candidate gene polymorphisms and alcoholism.