Electrocatalytic activity of DNA. Electrochemistry in Microscopic and Molecular Dimensions
| Authors | |
|---|---|
| Year of publication | 2002 |
| Type | Article in Proceedings |
| Conference | 53-rd Annual Meeting of the International Society of Electrochemistry.Symposium 3: Bioelectrochemistry. Book of Abstracts |
| Citation | |
| Field | Biophysics |
| Keywords | DNA; electrocatalytic activity of DNA; |
| Description | It has been shown, that a formation of a self-assembled monolayer of single-stranded thiol-terminated nucleotides (HS-ssDNA) on gold electrodes leads to a multifold increase of electrochemical signals from anionic red/ox marker, dissolved in aqueous solution. The measurements were performed by cyclovoltametry and impedance spectroscopy. Experimental conditions where the DNA-coupled electrocatalysis is observed were evaluated. A binding of double-stranded thiol-terminated DNA to gold electrodes does not provide any eletrocatalytic effect. DNA hybridisation in solution led to increase of electrochemical activity. |
| Related projects: |