Neuronal nitric oxide synthase (NOS1) gene polymorphism and IgE-mediated allergy in the Central European population
| Authors | |
|---|---|
| Year of publication | 2004 |
| Type | Article in Periodical |
| Magazine / Source | Allergy |
| MU Faculty or unit | |
| Citation | |
| Field | Genetics and molecular biology |
| Keywords | IgE; gene; polymorphism; allergy; NOS; nitric oxide |
| Description | Several findings suggest that nitric oxide (NO) plays a significant role in the regulation of the Th1/Th2 balance and contributes to the development of allergic diseases. Our study investigates a possible association of C/T transition located 276-bp downstream from the translation termination site in exon 29 of the human NOS1 gene with IgE-mediated allergic diseases in the Czech population. |
| Related projects: |