Microwave-assisted solvent-free synthesis of hexahydrochromeno[4,3-b]pyrroles

Warning

This publication doesn't include Institute of Computer Science. It includes Faculty of Science. Official publication website can be found on muni.cz.

Authors	POSPÍŠIL Jiří POTÁČEK Milan
Year of publication	2004
Type	Article in Periodical
Magazine / Source	European Journal of Organic Chemistry
MU Faculty or unit	Faculty of Science
Citation
Field	Organic chemistry
Keywords	cycloaddition; microwave-assisted synthesis; solvent-free synthesis; ylides
Description	Microwave-assisted solvent-free synthesis of hexahydrochromeno[4,3-b]pyrroles is reported. Intramolecular 1,3-dipolar cycloaddition under these conditions proceeds in 15 min with 80% yields. Moreover, pronounced steric requirements of alkyl substituents towards 1,3-dipolar cycloaddition are observed.
Related projects:	Chemical transformations activated by microwaves