K teorii senzitizace u látek vyvolávajících závislost

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Title in English Drugs of abuse sensitization theory
Authors

NOVÁKOVÁ Jana ŠULCOVÁ Alexandra

Year of publication 2004
Type Article in Periodical
Magazine / Source Adiktologie
MU Faculty or unit

Faculty of Medicine

Citation
Field Pharmacology and pharmaceutical chemistry
Keywords behavioural sensitization-drug dependence-dopamine
Description The study presented brings a summarized view to the behavioural sensitization phenomenon frequently referred coherently with drug dependence. There are circumscribed both sensitization and tolerance which used to be often associated with drug dependence. Furthermore, terminological notes concerning to sensitization are explained and its neurobiological basis is outlined, especially pharmacodynamic changes which can underlie sensitization. Particularly, attention is focused on the changes of dopaminergic neurotransmitter system plasticity.
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