Heart rate and increased intravascular volume

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Authors

SOUČEK Miroslav KÁRA Tomáš JURÁK Pavel HALÁMEK Josef ŠPINAROVÁ Lenka MELUZÍN Jaroslav TOMAN Jiří ŘIHÁČEK Ivan ŠUMBERA Josef FRÁŇA Petr

Year of publication 2003
Type Article in Periodical
Magazine / Source Physiol. Research
MU Faculty or unit

Faculty of Medicine

Citation
Field Cardiovascular diseases incl. cardiosurgery
Keywords kidneys; heart rate; atrial mechanisms; intravascular volume; breathing
Description The objective was to establish whether an intravascular volume increase leads to a heart rate (HR) incerase without increased sympahetic tonus. HR changes at rest and at deep breathing (6/min - simulated increase of atrial filling pressure) were measured in patients after heart transplantation. Evaluation of dependency of HR changes on breathing depth was done through a new time series methodology. The data was evaluated through graphs displaying a significant increase in the graph area at deep breathing, when compared with breathing at rest (p<0.01). We presume that an incease in HR corresponds to increased intravascular volume and malfunctioning kidneys.
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