Distribution of ionic concentrations in tubular system of cardiomyocytes

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Authors

ŠIMURDA Jiří PÁSEK Michal CHRISTÉ Georges ŠIMURDOVÁ Milena

Year of publication 2004
Type Article in Proceedings
Conference Analysis of Biomedical Signals and Images
MU Faculty or unit

Faculty of Medicine

Citation
Field Biophysics
Keywords cardiac cell; tubular system; quantitative modelling
Description To calculate distribution of ionic concentrations in t-tubular system of cardiac myocytes we proposed a model described by partial differential equations. Assumption of Ca2+ binding on or adjacent to the tubular membrane led to prominent delay in propagation of concentration changes of Ca2+ within the t-tubules.
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