Transcriptome of Treponema pallidum: gene expression profile during experimental rabbit infection.

• Authors: ŠMAJS David; MCKEVITT M.; HOWELL J.K.; NORRIS S.J.; CAI W.W.; PALZKILL T.; WEINSTOCK G.M.
• Year of publication: 2005
• Type: Article in Periodical
• Magazine / Source: J. Bacteriol
• MU Faculty or unit: Faculty of Medicine
• Field: Genetics and molecular biology
• Keywords: Treponema pallidum; expression profiling
• Description: RNA transcript levels in the syphilis spirochete Treponema pallidum subsp. pallidum (Nichols) isolated from experimentally infected rabbits were determined using DNA microarray technology. Characterization of the T. pallidum transcriptome during experimental infection provides further insight into the importance of gene expression levels in the survival and pathogenesis of this bacterium.

Related projects

• Postgenomic studies on Treponema pallidum, the syphilis spirochete
• Komparativní genomika patogenních spirochet rodu Treponema: cesta k sekvenčně specifické diagnostice