A Method for Detecting Breakpoints in Array CGH data
| Authors | |
|---|---|
| Year of publication | 2005 |
| Type | Article in Proceedings |
| Conference | EnviroInfo Brno 2005. Networking Environmental Information. Part 2. Proceedings of the 19th International Conference Informatics for Environmental Protection. |
| MU Faculty or unit | |
| Citation | |
| Field | Applied statistics, operation research |
| Keywords | array CGH; breakpoint detection; analysis; microarray |
| Description | In present, microarray CGH experiments became a powerful technique for analysing changes in DNA, by comparing control DNA and DNA of interest. This is widely used for example in genome cancer or species distin-guishing studies. The method produce huge amount of data and special statistic techniques for detecting copy number changes regions are necessary. We propose a new method for detecting breakpoints in DNA. The performance of the method is demonstrated using publicly available data set. |
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