13C-Detected Experiments for Nucleic Acids
| Authors | |
|---|---|
| Year of publication | 2005 |
| Type | Article in Proceedings |
| Conference | 20th NMR Valtice |
| MU Faculty or unit | |
| Citation | |
| Field | Physical chemistry and theoretical chemistry |
| Keywords | NMR spectroscopy; direct carbon detection; nucleic acid |
| Description | The direct detection of carbon atoms offers an alternative method for obtaining their chemical shift values and/or data for investigation of the dynamics of nucleic acid bases. Furthermore, the chemical shifts of the amino nitrogen atoms whose protons are broadened beyond detection due to the exchange with water can be obtained using a 13C-detected 13C-15N correlation experiment. In the sugar moiety, the carbon detected experiments are suitable for obtaining 1H-13C correlations in the cases where the proton signal is obscured by the large water peak. |
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