Účinek antipsychotik na kognici

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Title in English	The effect of antipsychotics on cognition
Authors	ČEŠKOVÁ Eva
Year of publication	2005
Type	Article in Periodical
Magazine / Source	Remedia
MU Faculty or unit	Faculty of Medicine
Citation
Field	Psychiatry, sexuology
Keywords	cognitive deficiency; atypical antipsychotics; conventional antipsychotics; attention; memory; verbal fluency
Description	Atypical antipsychotics are currently the most widespread therapeutical approach to cognitive deficiency in schizophrenic disorder. They are significantly more effective in controlling cognitive deficiency compared with conventional antipsychotics. Neverthless, results of the studies conducted to date in this area are somewhat discordant, which could be explained by differences in drug dosage, length of follow-up, population studied (first episode, drug resistant schizophrenia)and cognitive assessment method used. Atypical antipsychotics do not vary significantly in general effect on cognition but differences were found in their effects on particular domains (attention and verbal fluency). In confirmed, these differences could be relevant to better understanding of interindividual variation in cognitive deficiency between patient with schizophrenic disorder.
Related projects:	Ověření a posouzení dynamiky profilu kognitivních funkcí u nemocných s depresivní a schizofrenní poruchou The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.