Cognitive performance in people with Parkinson's disease and mild or moderate depression: effects of dopamine agonists in an add-on to L-dopa therapy.

Rektorová,  Irena; Rektor,  Ivan; Bareš,  Martin; Dostál, V.; Ehler, Edvard; Hummelová,  Zuzana; Fiedler, J.; Klajblová, Hana; Kulišťák, P.; Ressner, P.; Svátová, J.; Urbánek, Karel; Velísková, J.

Cognitive performance in people with Parkinson's disease and mild or moderate depression: effects of dopamine agonists in an add-on to L-dopa therapy.

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Authors	REKTOROVÁ Irena REKTOR Ivan BAREŠ Martin DOSTÁL V. EHLER Edvard FANFRDLOVÁ Zuzana FIEDLER J. KLAJBLOVÁ Hana KULIŠŤÁK P. RESSNER P. SVÁTOVÁ J. URBÁNEK Karel VELÍSKOVÁ J.
Year of publication	2005
Type	Article in Periodical
Magazine / Source	European Journal of Neurology
MU Faculty or unit	Faculty of Medicine
Citation
Field	Neurology, neurosurgery, neurosciences
Keywords	cognitive; depression; dopamine receptor a agonists; Parkinson's disease
Description	Cognitive performance was studied in people with advanced Parkinson's disease and mild or moderate depression before and after 8 months of treatment with dopamine agonists (pramipexole and pergolige) in an add-on to L-dopa therapy. Both drugs were safe with regard to cognitive functioning in the studied group of patients.
Related projects:	The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions. Plasticity of Regulatory Mechanisms of the Central Nervous Systems