Genetics and pain perception
| Authors | |
|---|---|
| Year of publication | 2006 |
| Type | Article in Periodical |
| Magazine / Source | European Journal of Pain |
| MU Faculty or unit | |
| Citation | |
| Field | Neurology, neurosurgery, neurosciences |
| Keywords | pain genetics gene polymorphism acute |
| Description | Recent progress in molecular biology has enabled gene expression modulations in animal models using techniques of “knock-out”, “oligo-antisense” and viral vectors. First association studies using PCR method investigate the impact of so-called candidate genes on pain perception emerged in the last two years. The methods mentioned above thus enable investigations, at a molecular level, of which out of the approximately 30 thousand genes of the human genome may be involved in pain mediation, which of these are polymorphic and which polymorphisms are responsible for interindividual differences in pain perception. |
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