An immunohistochemical detection of IL-6 in DRG of the rat model of neuropathic pain
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| Year of publication | 2007 |
| Type | Appeared in Conference without Proceedings |
| MU Faculty or unit | |
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| Description | IL-6, a proinflammatory cytokine, is critically involved in a cascade of events leading to the development and maintenance of neuropathic pain after nerve injury. Both ipsi- and contralateral L4-L5 DRG display changes of IL6 immunostaining one week after spinal nerve ligation. Satellite glial cells and endothelial cells are important sources of IL-6 protein in DRG associated with nerve injury up to a week. |
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