Nestin expression in osteosarcomas and derivation of nestin/CD133 positive osteosarcoma cell lines.

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Authors	VESELSKÁ Renata HERMANOVÁ Markéta LOJA Tomáš CHLAPEK Petr ZAMBO Iva VESELÝ Karel ZITTERBART Karel ŠTĚRBA Jaroslav
Year of publication	2008
Type	Article in Periodical
Magazine / Source	BMC Cancer
MU Faculty or unit	Faculty of Science
Citation
Web	http://www.biomedcentral.com/1471-2407/8/300
Field	Oncology and hematology
Keywords	nestin; CD133; intermediate filaments; osteosarcoma; immunocytochemistry; immunohistochemistry; cancer stem cells
Description	Immunohistochemical and immunocytochemical methods demonstrate the expression of nestin, the intermediate filament protein class VI, in osteosarcomas. Osteosarcoma cell lines showing nestin+/CD133+ phenotype were successfully derived from these tumors.
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