Detection and treatment of molecular relapse in acute myeloid leukemia with RUNXa, CBFB, MLL gene translocations, or NPMI mutation. Frequent quantitative monitoring of molecular markers in different compartments and correlation with WT1 gene expression.

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Authors	DOUBEK Michael PALÁSEK Ivo POSPÍŠIL Z. STRUNCOVÁ S. DVOŘÁKOVÁ Dana BORSKÝ M. KLABUSAY Martin BRYCHTOVÁ Y. KREJČÍ Marta MAYER Jiří
Year of publication	2008
Type	Article in Periodical
Magazine / Source	Annals of Hematology
MU Faculty or unit	Faculty of Medicine
Citation
Field	Oncology and hematology
Keywords	ACUTE LYMPHOBLASTIC-LEUKEMIA; FUSION TRANSCRIPTS; PROGNOSTIC VALUE
Description	Frequent quantitative monitoring of fusion transcripts is useful for reliably predicting hematological relapse in AML patients. Treatment for molecular relapse of AML can be successful.
Related projects:	Jaroslav Hájek Center for Theoretical and Applied Statistics