Klinické a genetické markery u perzistentní formy hyperkinetické poruchy (ADHD): výsledky longitudiální studie
| Title in English | Clinical and genetic markers in adolescents with persistent form of ADHD: results of a longitudinal study |
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| Authors | |
| Year of publication | 2009 |
| Type | Article in Periodical |
| Magazine / Source | Psychiatrie |
| MU Faculty or unit | |
| Citation | |
| Field | Psychiatry, sexuology |
| Keywords | ADHD DNA polymorphism genetic adolescents persistent form |
| Description | Within a follow-up of an association study, in which polymorphisms of selected genes in 119 boys diagnosed with ADHD (aged 7 to 13) as well as in a control group were analyzed, clinical and genetic markers in 40 adolescents aged 14 to 18 were studied in the context of the persistent form of ADHD. The relationship between TaqI polymorphism of the DRD2 gene (newly ANKK1 gene polymorphism) and ADHD was confirmed and newly the relationship between ADHD and polymorphisms of 5-HTT and DRD5 genes was found. Remissions correlated with the polymorphisms of the IL-6 and ACE genes. Increased impulsivity in adolescence was found. |
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