HOTSPOT WIZARD 1.0

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This publication doesn't include Institute of Computer Science. It includes Faculty of Science. Official publication website can be found on muni.cz.

Authors	PAVELKA Antonín CHOVANCOVÁ Eva DAMBORSKÝ Jiří
Year of publication	2008
MU Faculty or unit	Faculty of Science
Web	Počítačový program pro racionální design mutací
Description	HotSpot Wizard is a tool for automatic identification of hot spot sites for engineering of substrate specificity, activity or enantioselectivity of enzymes. HotSpot Wizard integrates several bioinformatics databases and computational tools and represents an easy way to perform several structural and evolutionary analyses at once with minimal demands on users, making this server potentially useful for experimentalists with no prior knowledge of computer modelling or rational protein design.
Related projects:	Interactions among the chemicals, environment and biological systems and their consequences on the global, regional and local scales (INCHEMBIOL) New approaches in electrochemical analysis of nucleic acids and oligonucleotides aimed at a ultrasensitive microdetection of DNA and DNA hybridization Center of Biocatalysis and Biotransformation Visualization of protein structures