Expression pattern of HLA class I antigens in renal cell carsinoma and primary cell line cultures: Methodological implications for immunotherapy

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Authors	HANÁK Libor SLABÝ Ondřej LAUEROVÁ Ludmila KŘEN Leoš NENUTIL Rudolf MICHÁLEK Jaroslav
Year of publication	2009
Type	Article in Periodical
Magazine / Source	Medical Science Monitor (International Medical Journal of Experimental and Clinical Research)
MU Faculty or unit	Faculty of Medicine
Citation
Field	Oncology and hematology
Keywords	renal carcinoma; immunotherapy; HLA antigens
Description	In this study both classic and non-classic HLA cals I antigens were tested in tumor specimens and estabilished primary cell cultures derived from renal cell carcinoma patients. Our findings suggest that primary cell line cultures derived from surgical specimens of renal cell carcinomas are a feasible model for immunotherapy research through their high cultivation protential.
Related projects:	Bezpečná biotechnologie alotransplatovaných hematopoetických kmenových buněk u vybraných solidních a hematologických nádorů jako adoptivní imunoterapie