Vývoj radiometrických metod pro stanovení enzymových aktivit jodothyronin dejodas: Vliv antidepresiva fluoxetinu na aktivity dejodas typu 1, 2 a 3 v mozku potkana
| Title in English | Development of radiometric methods for determination of enzyme activities of iodothyronine deiodinases: The influence of antidepressant drug fluoxetine on the types 1, 2 and 3 deiodinase activities in the rat brain |
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| Authors | |
| Year of publication | 2010 |
| Type | Article in Proceedings |
| Conference | Radioanalytické metody IAA 09 (Vobecký M., ed.) |
| MU Faculty or unit | |
| Citation | |
| web | http://www.spektroskopie.cz |
| Field | Pharmacology and pharmaceutical chemistry |
| Keywords | Antidepressant drug; deiodinase; radiometric assay |
| Description | The objectives of the present study were to establish valid assay conditions for measurement of the types 1, 2 and 3 iodothyronine deiodinases activities, and to use the radiometric enzyme assays especially to follow the effects of antidepressant drug fluoxetine (Prozac) on the metabolism of thyroid hormones in the rat. |
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