Baroreflex sensitivity is reduced in obese normotensive children and adolescents

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Authors	LAZAROVA Zuzana TONHAJZEROVA Ingrid TRUNKVALTEROVA Zuzana BROZMANOVA Andrea HONZÍKOVÁ Nataša JAVORKA Kamil BAUMERT Mathias JAVORKA Michal
Year of publication	2009
Type	Article in Periodical
Magazine / Source	CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
MU Faculty or unit	Faculty of Medicine
Citation
Field	Physiology
Keywords	baroreflex sensitivity; obesity; blood pressure; autonomic nervous system; children and adolescents
Description	V jazyce výsledku Baroreflex sensitivity was evaluated in 20 obese children and adolescents in comparison with 20 age-and sex-matched nonobese subjects. All subjects were examined in the supine position over a period of 50 min. Systolic blood pressure (SBP) and RR intervals were monitored continuously. Baroreflex sensitivity (BRS) was assessed by crossspectral analysis of SBP and RR interval oscillations at 0.1 Hz in 3 time intervals of 3 min each. The BRS index was significantly lower in obese children and adolescents than in the nonobese control group (p = 0.002). Significant changes in the BRS index over time (p = 0.004) were found only in nonobese subjects.
Related projects:	Early diagnostics and treatment of cardiovascular diseases