Pacientka s AL- amyloidózou a závažným deficitem faktoru X je po vysokodávkované chemoterapii již 7 let v kompletní hematologické remisi s normální aktivitou faktoru X. Popis případu a přehled literatury

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Title in English	A patient with AL amyloidosis and severe factor X deficiency has been in complete haematological remission with normal factor X activity for 7 years following high-dose chemotherapy. A case study and literature review
Authors	ADAM Zdeněk MATÝŠKOVÁ M. KREJČÍ Marta POUR Luděk KISSOVÁ J. ŠLECHTOVÁ M. CHLUPOVÁ G. STAVAŘOVÁ Yveta SIMONIDES Jan PENKA Miroslav MAYER Jiří HÁJEK Roman
Year of publication	2010
Type	Article in Periodical
Magazine / Source	Vnitřní lékařství
MU Faculty or unit	Faculty of Medicine
Citation
Field	Oncology and hematology
Keywords	factor X - AL amyloidosis;multiple myeloma;monoclonal gammopathy;high-dose chemotherapy
Description	In this paper are described a frequent complications of AL amyloidosis: disturbance of haemostasis and bleeding. These are frequently caused by increased fragility of capillaries, thrombocyte function disorders and coagulation cascade defects.
Related projects:	University Research Centre - Czech Myeloma Group From classic prognostic markers to clinical applications in selected pharmacogenomic and pharmacoproteomic projects in multiple myeloma and monoclonal gammapathies