Funkční deficit pentózového cyklu jako důsledek abnormálního metabolizmu thiaminu ve vztahu k progresi diabetické nefropatie a k mortalitě

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Title in English Functionally deficient pentose phosphate pathway as a result of abnormal thiamine metabolism in relation to the progression of diabetic nephropathy and mortality
Authors

PÁCAL Lukáš TOMANDL Josef SVOJANOVSKÝ Jan KRUSOVÁ Darja ŠTĚPÁNKOVÁ Soňa OLŠOVSKÝ Jindřich BĚLOBRÁDKOVÁ Jana TANHÄUSEROVÁ Veronika TOMANDLOVÁ Marie ŘEHOŘOVÁ Jitka SMRŽOVÁ Jana HERTLOVÁ Miluše MUŽÍK Jan KAŇKOVÁ Kateřina

Year of publication 2010
Type Conference abstract
MU Faculty or unit

Faculty of Medicine

Citation
Description Pentose phosphate pathway (PPP) represents a potentially protective pathway in hyperglycemia. Transketolase is the key enzyme of PPP. We aimed to find out whether parameters of thiamine metabolism can influence progression of diabetic nephropathy (DN) and morbidity of patients with DN.
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