Koncentrace hepatocytárního růstového faktoru a trombospondinu predikuje léčebnou odpověď u pacientů s mnohočetným myelomem

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Title in English	Concentration of hepatocyte growth factor and thrombospondin predict treatment response in patients with multiple myeloma
Authors	ŠVÁCHOVÁ Hana POUR Luděk ALMÁŠI Martina NĚMEC Pavel KRÁLOVÁ Dana KOVÁŘOVÁ Lucie PENKA Miroslav VORLÍČEK Jiří HÁJEK Roman
Year of publication	2010
Type	Article in Periodical
Magazine / Source	Transfuze a hematologie dnes
MU Faculty or unit	Faculty of Medicine
Citation
Field	Oncology and hematology
Keywords	multiple myeloma; angiogenesis; HGF; thrombospondin; bortezomib
Description	Multiple myeloma is hematological malignancy in which has been demonstrated increased level of angiogenesis. We ratified hypothesis that high levels of thrombospondin and low levels of HGF correlate with a good response after bortezomib treatment.
Related projects:	University Research Centre - Czech Myeloma Group From classic prognostic markers to clinical applications in selected pharmacogenomic and pharmacoproteomic projects in multiple myeloma and monoclonal gammapathies