Antiepileptika v psychiatrii

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Title in English Antiepileptics in psychiatry
Authors

ČEŠKOVÁ Eva

Year of publication 2010
Type Article in Periodical
Magazine / Source Neurologie pro praxi
MU Faculty or unit

Faculty of Medicine

Citation
Field Psychiatry, sexuology
Keywords antiepileptics; bipolar disorder; mood stabilizers; atypical antipsychotics; combination
Description based on controlled studies valproate, carbamazepine and lamotrigine have a firm position in the treatment of bipolar disorder. Besides lithium thy are considered to be the most important representatives of mood stabilizers (MS)- According to available quidelines MS are recommended in all phases of bipolar disorder. The aim of this retrospective study was to assess the treatment of bipolar disorder in clinical practice. Analylzing charts of patients we found that totally 71 patients (37 female, 34 male) were hospitalized 92 times (35 with mania, 53 with depression) during the 2-year period. in both mania and depression the most frequently used treatment strategy was the combination of MSand atypical antipsychotic. this is corresponding with the data about a more robust effect of combination in severe disorders requiring hospitalization. the most frequently used MS was valproate, the most frequently used antipsychotics were olanzapine and quetiapine.
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